Prozone phenomenon in secondary syphilis

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Wendkebach phenomenon occurring in secondary syphilis.

Cardiac involvement in late syphilis is a relatively common occurrence and is a consequence of syphilitic aortitis, or rarely of gummatous lesions of the myocardium. Not so well known is the fact that cardiac manifestations in the form of abnormalities of the electrocardiogram may occur in early syphilis. Steiger and Edeiken (1948) recorded electrocardiographic abnormalities in 50 per cent. of ...

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Rh ANTIBODIES AND THE PROZONE PHENOMENON BY

In 1942 Taylor, Race, Prior, and Ikin reported an anti-Rh serum which failed to agglutinate Rhpositive cells in saline suspension except when diluted. They thought that this prozone was due to antigen and antibody not being present in optimal proportions, and that the mechanism was similar to that of the zones that occur in precipitation reactions. Wiener (1944) described incomplete Rh antibodi...

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Rh antibodies and the prozone phenomenon.

In 1942 Taylor, Race, Prior, and Ikin reported an anti-Rh serum which failed to agglutinate Rhpositive cells in saline suspension except when diluted. They thought that this prozone was due to antigen and antibody not being present in optimal proportions, and that the mechanism was similar to that of the zones that occur in precipitation reactions. Wiener (1944) described incomplete Rh antibodi...

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Incidence and risk factors for the prozone phenomenon in serologic testing for syphilis in a large cohort.

BACKGROUND The prozone phenomenon is known to be associated with high antibody titers; other associations, such as host factors, have not been elucidated. METHODS A retrospective analysis was conducted to evaluate the incidence of the prozone phenomenon of the syphilis rapid plasma reagin (RPR) test among 46 856 clinical samples, between June 2010 and June 2013. Logistic regression was used t...

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Secondary Syphilis

A 27-year-old black woman presented with complaints of skin lesions on the vulva, back, nipple and ear. Darkfield examination of the cxudate from the moist vulvar papules (A) revealed motile spirochetes. A VDRL was reactive at a titer of 1:1,024. A papular lesion with raised borders (annular syphilid) (B) was discovered during examination of the back. Split papules were also discovered on the n...

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ژورنال

عنوان ژورنال: Indian Journal of Sexually Transmitted Diseases and AIDS

سال: 2011

ISSN: 0253-7184

DOI: 10.4103/0253-7184.81256